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Specificity in substrate and cofactor recognition by the N-terminal domain of the chaperone ClpX

Clp ATPases are a unique group of ATP-dependent chaperones supporting targeted protein unfolding and degradation in concert with their respective proteases. ClpX is a representative member of these ATPases; it consists of two domains, a zinc-binding domain (ZBD) that forms dimers and a AAA(+) ATP-bi...

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Detalles Bibliográficos
Main Authors: Thibault, Guillaume, Yudin, Jovana, Wong, Philip, Tsitrin, Vladimir, Sprangers, Remco, Zhao, Rongmin, Houry, Walid A.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1693814/
https://ncbi.nlm.nih.gov/pubmed/17090685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0601505103
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