The Protein Chaperone ClpX Targets Native and Non-native Aggregated Substrates for Remodeling, Disassembly, and Degradation with ClpP

ClpX is a member of the Clp/Hsp100 family of ATP-dependent chaperones and partners with ClpP, a compartmentalized protease, to degrade protein substrates bearing specific recognition signals. ClpX targets specific proteins for degradation directly or with substrate-specific adaptor proteins. Native...

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Vydáno v:Front Mol Biosci
Hlavní autoři: LaBreck, Christopher J., May, Shannon, Viola, Marissa G., Conti, Joseph, Camberg, Jodi L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Molecular Biosciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5415555/
https://ncbi.nlm.nih.gov/pubmed/28523271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2017.00026
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