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Epigenetic asymmetry in the mammalian zygote and early embryo: relationship to lineage commitment?

Epigenetic asymmetry between parental genomes and embryonic lineages exists at the earliest stages of mammalian development. The maternal genome in the zygote is highly methylated in both its DNA and its histones and most imprinted genes have maternal germline methylation imprints. The paternal geno...

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Bibliografski detalji
Glavni autori: Reik, Wolf, Santos, Fatima, Mitsuya, Kohzoh, Morgan, Hugh, Dean, Wendy
Format: Artigo
Jezik:Inglês
Izdano: 2003
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1693238/
https://ncbi.nlm.nih.gov/pubmed/14511488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2003.1326
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