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Epigenetic asymmetry in the mammalian zygote and early embryo: relationship to lineage commitment?
Epigenetic asymmetry between parental genomes and embryonic lineages exists at the earliest stages of mammalian development. The maternal genome in the zygote is highly methylated in both its DNA and its histones and most imprinted genes have maternal germline methylation imprints. The paternal geno...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1693238/ https://ncbi.nlm.nih.gov/pubmed/14511488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2003.1326 |
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