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Small-molecule therapeutics for the treatment of glycolipid lysosomal storage disorders.

Glycosphingolipid (GSL) lysosomal storage disorders are a small but challenging group of human diseases to treat. Although these disorders appear to be monogenic in origin, where the catalytic activity of enzymes in GSL catabolism is impaired, the clinical presentation and severity of disease are he...

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Bibliografische gegevens
Hoofdauteurs: Butters, Terry D, Mellor, Howard R, Narita, Keishi, Dwek, Raymond A, Platt, Frances M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2003
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1693180/
https://ncbi.nlm.nih.gov/pubmed/12803927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2003.1278
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