The guanylate binding protein-1 GTPase controls the invasive and angiogenic capability of endothelial cells through inhibition of MMP-1 expression

Expression of the large GTPase guanylate binding protein-1 (GBP-1) is induced by inflammatory cytokines (ICs) in endothelial cells (ECs), and the helical domain of the molecule mediates the repression of EC proliferation by ICs. Here we show that the expression of GBP-1 and of the matrix metalloprot...

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Main Authors: Guenzi, Eric, Töpolt, Kristin, Lubeseder-Martellato, Clara, Jörg, Anita, Naschberger, Elisabeth, Benelli, Roberto, Albini, Adriana, Stürzl, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC169055/
https://ncbi.nlm.nih.gov/pubmed/12881412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg382
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