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The helical domain of GBP-1 mediates the inhibition of endothelial cell proliferation by inflammatory cytokines

Inflammatory cytokines (IC) activate endothelial cell adhesiveness for monocytes and inhibit endothelial cell growth. Here we report the identification of the human guanylate binding protein-1 (GBP-1) as the key and specific mediator of the anti-proliferative effect of IC on endothelial cells. GBP-1...

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Hlavní autoři: Guenzi, Eric, Töpolt, Kristin, Cornali, Emmanuelle, Lubeseder-Martellato, Clara, Jörg, Anita, Matzen, Kathrin, Zietz, Christian, Kremmer, Elisabeth, Nappi, Filomena, Schwemmle, Martin, Hohenadl, Christine, Barillari, Giovanni, Tschachler, Erwin, Monini, Paolo, Ensoli, Barbara, Stürzl, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2001
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC125279/
https://ncbi.nlm.nih.gov/pubmed/11598000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.20.5568
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