Wird geladen...

Nuclear factor-kappaB motif and interferon-alpha-stimulated response element co-operate in the activation of guanylate-binding protein-1 expression by inflammatory cytokines in endothelial cells.

The large GTPase GBP-1 (guanylate-binding protein-1) is a major IFN-gamma (interferon-gamma)-induced protein with potent anti-angiogenic activity in endothelial cells. An ISRE (IFN-alpha-stimulated response element) is necessary and sufficient for the induction of GBP-1 expression by IFN-gamma. Rece...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Naschberger, Elisabeth, Werner, Thomas, Vicente, Ana B, Guenzi, Eric, Töpolt, Kristin, Leubert, René, Lubeseder-Martellato, Clara, Nelson, Peter J, Stürzl, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224089/
https://ncbi.nlm.nih.gov/pubmed/14741045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031873
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!