Processing and secretion of guanylate binding protein‐1 depend on inflammatory caspase activity

Human guanylate binding protein‐1 (GBP‐1) belongs to the family of large GTPases. The expression of GBP‐1 is inducible by inflammatory cytokines, and the protein is involved in inflammatory processes and host defence against cellular pathogens. GBP‐1 is the first GTPase which was described to be sec...

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Bibliographic Details
Published in:J Cell Mol Med
Main Authors: Naschberger, Elisabeth, Geißdörfer, Walter, Bogdan, Christian, Tripal, Philipp, Kremmer, Elisabeth, Stürzl, Michael, Britzen‐Laurent, Nathalie
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2017
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571548/
https://ncbi.nlm.nih.gov/pubmed/28272793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13116
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