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DNA binding and cleavage by the periplasmic nuclease Vvn: a novel structure with a known active site

The Vibrio vulnificus nuclease, Vvn, is a non-specific periplasmic nuclease capable of digesting DNA and RNA. The crystal structure of Vvn and that of Vvn mutant H80A in complex with DNA were resolved at 2.3Å resolution. Vvn has a novel mixed α/β topology containing four disulfide bridges, suggestin...

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Autors principals: Li, Chia-Lung, Hor, Lien-I, Chang, Zee-Fen, Tsai, Li-Chu, Yang, Wei-Zen, Yuan, Hanna S.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC169050/
https://ncbi.nlm.nih.gov/pubmed/12881435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg377
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