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DNA binding and cleavage by the periplasmic nuclease Vvn: a novel structure with a known active site
The Vibrio vulnificus nuclease, Vvn, is a non-specific periplasmic nuclease capable of digesting DNA and RNA. The crystal structure of Vvn and that of Vvn mutant H80A in complex with DNA were resolved at 2.3Å resolution. Vvn has a novel mixed α/β topology containing four disulfide bridges, suggestin...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2003
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC169050/ https://ncbi.nlm.nih.gov/pubmed/12881435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg377 |
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