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Gene Expression Profiles Distinguish the Carcinogenic Effects of Aristolochic Acid in Target (Kidney) and Non-target (Liver) Tissues in Rats

BACKGROUND: Aristolochic acid (AA) is the active component of herbal drugs derived from Aristolochia species that have been used for medicinal purposes since antiquity. AA, however, induced nephropathy and urothelial cancer in people and malignant tumors in the kidney and urinary tract of rodents. A...

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Главные авторы: Chen, Tao, Guo, Lei, Zhang, Lu, Shi, Leming, Fang, Hong, Sun, Yongming, Fuscoe, James C, Mei, Nan
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2006
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1683578/
https://ncbi.nlm.nih.gov/pubmed/17118142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-7-S2-S20
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