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DNA adduct formation and mutation induction by aristolochic acid in rat kidney and liver

Aristolochic acid (AA) is a potent nephrotoxin and carcinogen and is the causative factor for Chinese herb nephropathy. AA has been associated with the development of urothelial cancer in humans, and kidney and forestomach tumors in rodents. To investigate the molecular mechanisms responsible for th...

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發表在:Mutat Res
Main Authors: Mei, Nan, Arlt, Volker M., Phillips, David H., Heflich, Robert H., Chen, Tao
格式: Artigo
語言:Inglês
出版: 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370021/
https://ncbi.nlm.nih.gov/pubmed/17010389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2006.08.004
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