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DNA adduct formation and mutation induction by aristolochic acid in rat kidney and liver

Aristolochic acid (AA) is a potent nephrotoxin and carcinogen and is the causative factor for Chinese herb nephropathy. AA has been associated with the development of urothelial cancer in humans, and kidney and forestomach tumors in rodents. To investigate the molecular mechanisms responsible for th...

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Библиографические подробности
Опубликовано в: :Mutat Res
Главные авторы: Mei, Nan, Arlt, Volker M., Phillips, David H., Heflich, Robert H., Chen, Tao
Формат: Artigo
Язык:Inglês
Опубликовано: 2006
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370021/
https://ncbi.nlm.nih.gov/pubmed/17010389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2006.08.004
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