Analysis of gene expression changes in relation to toxicity and tumorigenesis in the livers of Big Blue transgenic rats fed comfrey (Symphytum officinale)

BACKGROUND: Comfrey is consumed by humans as a vegetable and a tea, and has been used as an herbal medicine for more than 2000 years. Comfrey, however, is hepatotoxic in livestock and humans and carcinogenic in experimental animals. Our previous study suggested that comfrey induces liver tumors by a...

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Autori principali: Mei, Nan, Guo, Lei, Zhang, Lu, Shi, Leming, Sun, Yongming Andrew, Fung, Chris, Moland, Carrie L, Dial, Stacey L, Fuscoe, James C, Chen, Tao
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2006
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Proceedings
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1683566/
https://ncbi.nlm.nih.gov/pubmed/17118137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-7-S2-S16
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