Analysis of gene expression changes in relation to toxicity and tumorigenesis in the livers of Big Blue transgenic rats fed comfrey (Symphytum officinale)

BACKGROUND: Comfrey is consumed by humans as a vegetable and a tea, and has been used as an herbal medicine for more than 2000 years. Comfrey, however, is hepatotoxic in livestock and humans and carcinogenic in experimental animals. Our previous study suggested that comfrey induces liver tumors by a...

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Detalhes bibliográficos
Main Authors: Mei, Nan, Guo, Lei, Zhang, Lu, Shi, Leming, Sun, Yongming Andrew, Fung, Chris, Moland, Carrie L, Dial, Stacey L, Fuscoe, James C, Chen, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Proceedings
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1683566/
https://ncbi.nlm.nih.gov/pubmed/17118137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-7-S2-S16
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