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Gene expression changes induced by the tumorigenic pyrrolizidine alkaloid riddelliine in liver of Big Blue rats

BACKGROUND: Pyrrolizidine alkaloids (PAs) are probably the most common plant constituents that poison livestock, wildlife, and humans worldwide. Riddelliine is isolated from plants grown in the western United States and is a prototype of genotoxic PAs. Riddelliine was used to investigate the genotox...

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Detalhes bibliográficos
Main Authors: Mei, Nan, Guo, Lei, Liu, Ruqing, Fuscoe, James C, Chen, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099496/
https://ncbi.nlm.nih.gov/pubmed/18047727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-8-S7-S4
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