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Adult and infantile glycogenosis type II in one family, explained by allelic diversity.

To define the cause of clinical heterogeneity in glycogenosis type II we have studied the inheritance and molecular nature of acid alpha-glucosidase deficiency in a rare family with severe infantile as well as mild late-onset variants of this disease. The (mutant) acid alpha-glucosidase alleles of c...

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Main Authors: Hoefsloot, L H, van der Ploeg, A T, Kroos, M A, Hoogeveen-Westerveld, M, Oostra, B A, Reuser, A J
Format: Artigo
Jezik:Inglês
Izdano: 1990
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1683537/
https://ncbi.nlm.nih.gov/pubmed/2403755
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