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Enzyme therapy and immune response in relation to CRIM status: the Dutch experience in classic infantile Pompe disease

BACKGROUND: Enzyme-replacement therapy (ERT) in Pompe disease—an inherited metabolic disorder caused by acid α-glucosidase deficiency and characterized in infants by generalized muscle weakness and cardiomyopathy—can be complicated by immune responses. Infants that do not produce any endogenous acid...

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Detalhes bibliográficos
Publicado no:J Inherit Metab Dis
Main Authors: van Gelder, Carin M., Hoogeveen-Westerveld, Marianne, Kroos, Marian A., Plug, Iris, van der Ploeg, Ans T., Reuser, Arnold J. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4341007/
https://ncbi.nlm.nih.gov/pubmed/24715333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10545-014-9707-6
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