Expression and routeing of human lysosomal alpha-glucosidase in transiently transfected mammalian cells.

Previously isolated lysosomal alpha-glucosidase cDNA clones were ligated to full-length constructs for expression in vitro and in mammalian cells. One of these constructs (pSHAG1) did not code for functional enzyme, due to an arginine residue instead of a tryptophan residue at amino acid position 40...

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Main Authors: Hoefsloot, L H, Willemsen, R, Kroos, M A, Hoogeveen-Westerveld, M, Hermans, M M, Van der Ploeg, A T, Oostra, B A, Reuser, A J
Format: Artigo
Sprog:Inglês
Udgivet: 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1149726/
https://ncbi.nlm.nih.gov/pubmed/2268275
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