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Two-locus models of disease: comparison of likelihood and nonparametric linkage methods.

The power to detect linkage for likelihood and nonparametric (Haseman-Elston, affected-sib-pair, and affected-pedigree-member) methods is compared for the case of a common, dichotomous trait resulting from the segregation of two loci. Pedigree data for several two-locus epistatic and heterogeneity m...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Goldin, L R, Weeks, D E
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1993
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1682376/
https://ncbi.nlm.nih.gov/pubmed/8213819
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