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Comparison of nonparametric statistics for detection of linkage in nuclear families: single-marker evaluation.

We have evaluated 23 different statistics, from a total of 10 popular software packages for model-free linkage analysis of nuclear-family data, by applying them to single-marker data simulated under several two-locus disease models. The statistics that we examined fall into two broad categories: (1)...

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Autors principals: Davis, S, Weeks, D E
Format: Artigo
Idioma:Inglês
Publicat: 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1716077/
https://ncbi.nlm.nih.gov/pubmed/9399893
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