Nonparametric simulation-based statistics for detecting linkage in general pedigrees.

We present here four nonparametric statistics for linkage analysis that test whether pairs of affected relatives share marker alleles more often than expected. These statistics are based on simulating the null distribution of a given statistic conditional on the unaffecteds' marker genotypes. E...

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Bibliographic Details
Main Authors: Davis, S., Schroeder, M., Goldin, L. R., Weeks, D. E.
Format: Artigo
Language:Inglês
Published: 1996
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1914666/
https://ncbi.nlm.nih.gov/pubmed/8644751
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