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Parametric and nonparametric multipoint linkage analysis with imprinting and two-locus-trait models: application to mite sensitization.

We present two extensions to linkage analysis for genetically complex traits. The first extension allows investigators to perform parametric (LOD-score) analysis of traits caused by imprinted genes-that is, of traits showing a parent-of-origin effect. By specification of two heterozygote penetrance...

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Detalhes bibliográficos
Main Authors: Strauch, K, Fimmers, R, Kurz, T, Deichmann, K A, Wienker, T F, Baur, M P
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1378058/
https://ncbi.nlm.nih.gov/pubmed/10796874
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