Correction of hemophilia as a proof of concept for treatment of monogenic diseases by fetal spleen transplantation

Previous clinical attempts to correct genetic deficiencies such as hemophilia or Gaucher disease by transplantation of allogeneic spleen were associated with aggressive graft versus host disease, mediated by mature T cells derived from the donor spleen. We show that a fetal pig spleen harvested at t...

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Bibliografiset tiedot
Päätekijät: Aronovich, Anna, Tchorsh, Dalit, Katchman, Helena, Eventov-Friedman, Smadar, Shezen, Elias, Martinowitz, Uri, Blazar, Bruce R., Cohen, Sivan, Tal, Orna, Reisner, Yair
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2006
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1682010/
https://ncbi.nlm.nih.gov/pubmed/17148607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607012103
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