Correction of hemophilia as a proof of concept for treatment of monogenic diseases by fetal spleen transplantation

Previous clinical attempts to correct genetic deficiencies such as hemophilia or Gaucher disease by transplantation of allogeneic spleen were associated with aggressive graft versus host disease, mediated by mature T cells derived from the donor spleen. We show that a fetal pig spleen harvested at t...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Aronovich, Anna, Tchorsh, Dalit, Katchman, Helena, Eventov-Friedman, Smadar, Shezen, Elias, Martinowitz, Uri, Blazar, Bruce R., Cohen, Sivan, Tal, Orna, Reisner, Yair
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2006
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1682010/
https://ncbi.nlm.nih.gov/pubmed/17148607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607012103
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