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The promoters of human cell cycle genes integrate signals from two tumor suppressive pathways during cellular transformation

Deciphering regulatory events that drive malignant transformation represents a major challenge for systems biology. Here, we analyzed genome-wide transcription profiling of an in vitro cancerous transformation process. We focused on a cluster of genes whose expression levels increased as a function...

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Detalhes bibliográficos
Main Authors: Tabach, Yuval, Milyavsky, Michael, Shats, Igor, Brosh, Ran, Zuk, Or, Yitzhaky, Assif, Mantovani, Roberto, Domany, Eytan, Rotter, Varda, Pilpel, Yitzhak
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1681464/
https://ncbi.nlm.nih.gov/pubmed/16729057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb4100030
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