Amplification of the 20q Chromosomal Arm Occurs Early in Tumorigenic Transformation and May Initiate Cancer

Duplication of chromosomal arm 20q occurs in prostate, cervical, colon, gastric, bladder, melanoma, pancreas and breast cancer, suggesting that 20q amplification may play a causal role in tumorigenesis. According to an alternative view, chromosomal imbalance is mainly a common side effect of cancer...

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Autores principales: Tabach, Yuval, Kogan-Sakin, Ira, Buganim, Yosef, Solomon, Hilla, Goldfinger, Naomi, Hovland, Randi, Ke, Xi-Song, Oyan, Anne M., Kalland, Karl-H., Rotter, Varda, Domany, Eytan
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031497/
https://ncbi.nlm.nih.gov/pubmed/21297939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014632
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