Amplification of the 20q Chromosomal Arm Occurs Early in Tumorigenic Transformation and May Initiate Cancer

Duplication of chromosomal arm 20q occurs in prostate, cervical, colon, gastric, bladder, melanoma, pancreas and breast cancer, suggesting that 20q amplification may play a causal role in tumorigenesis. According to an alternative view, chromosomal imbalance is mainly a common side effect of cancer...

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Autors principals: Tabach, Yuval, Kogan-Sakin, Ira, Buganim, Yosef, Solomon, Hilla, Goldfinger, Naomi, Hovland, Randi, Ke, Xi-Song, Oyan, Anne M., Kalland, Karl-H., Rotter, Varda, Domany, Eytan
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031497/
https://ncbi.nlm.nih.gov/pubmed/21297939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014632
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