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Amplification of the 20q Chromosomal Arm Occurs Early in Tumorigenic Transformation and May Initiate Cancer

Duplication of chromosomal arm 20q occurs in prostate, cervical, colon, gastric, bladder, melanoma, pancreas and breast cancer, suggesting that 20q amplification may play a causal role in tumorigenesis. According to an alternative view, chromosomal imbalance is mainly a common side effect of cancer...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tabach, Yuval, Kogan-Sakin, Ira, Buganim, Yosef, Solomon, Hilla, Goldfinger, Naomi, Hovland, Randi, Ke, Xi-Song, Oyan, Anne M., Kalland, Karl-H., Rotter, Varda, Domany, Eytan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031497/
https://ncbi.nlm.nih.gov/pubmed/21297939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014632
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