Coupling transcriptional and post-transcriptional miRNA regulation in the control of cell fate

miRNAs function as a critical regulatory layer in development, differentiation, and the maintenance of cell fate. Depletion of miRNAs from embryonic stem cells impairs their differentiation capacity. Total elimination of miRNAs leads to premature senescence in normal cells and tissues through activa...

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Detaylı Bibliyografya
Asıl Yazarlar: Shalgi, Reut, Brosh, Ran, Oren, Moshe, Pilpel, Yitzhak, Rotter, Varda
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2009
Konular:
Review
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815735/
https://ncbi.nlm.nih.gov/pubmed/20157565
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