Hormone binding induces rapid proteasome-mediated degradation of thyroid hormone receptors

The thyroid hormone 3,3′,5-triiodo-l-thyronine (T3) is essential for growth, differentiation, and development. Its biological activities are mediated by T3 nuclear receptors (TRs). At present, how T3 regulates TR proteins and the resulting functional consequences are still unknown. Immunofluorescenc...

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Podrobná bibliografie

Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Dace, Alexandra, Zhao, Li, Park, Kyung Soo, Furuno, T., Takamura, N., Nakanishi, M., West, Brian L., Hanover, John A., Cheng, Sheue-yann
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 2000
Témata:	Biological Sciences
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16808/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10908671/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.160257997
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