Hormone binding induces rapid proteasome-mediated degradation of thyroid hormone receptors

The thyroid hormone 3,3′,5-triiodo-l-thyronine (T3) is essential for growth, differentiation, and development. Its biological activities are mediated by T3 nuclear receptors (TRs). At present, how T3 regulates TR proteins and the resulting functional consequences are still unknown. Immunofluorescenc...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Dace, Alexandra, Zhao, Li, Park, Kyung Soo, Furuno, T., Takamura, N., Nakanishi, M., West, Brian L., Hanover, John A., Cheng, Sheue-yann
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 2000
Fag:	Biological Sciences
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16808/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10908671/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.160257997
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