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A systematic exploration of the influence of the protein stability on amyloid fibril formation in vitro

There are a number of diseases in which normally soluble proteins associate into regular, insoluble amyloid fibrils. The development of in vitro model systems in which detailed structural, kinetic, and thermodynamic characterization are feasible is of critical importance to our understanding of the...

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Autors principals: Ramírez-Alvarado, Marina, Merkel, Jane S., Regan, Lynne
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC16807/
https://ncbi.nlm.nih.gov/pubmed/10908649
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