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Butyrylcholinesterase attenuates amyloid fibril formation in vitro

In Alzheimer’s disease, both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) colocalize with brain fibrils of amyloid-β (Aβ) peptides, and synaptic AChE-S facilitates fibril formation by association with insoluble Aβ fibrils. Here, we report that human BChE and BSP41, a synthetic peptid...

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Detalhes bibliográficos
Main Authors: Diamant, Sophia, Podoly, Erez, Friedler, Assaf, Ligumsky, Hagai, Livnah, Oded, Soreq, Hermona
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482631/
https://ncbi.nlm.nih.gov/pubmed/16731619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602922103
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