Immunization of Patients with Metastatic Melanoma Using Both Class I- and Class Ii-Restricted Peptides from Melanoma-Associated Antigens

Cancer vaccines targeting CD8(+) T cells have been successful in eliciting immunologic responses but disappointing in inducing clinical responses. Strong evidence supports the importance of CD4(+) T cells in “helping” cytotoxic CD8(+) cells in antitumor immunity. We report here on two consecutive cl...

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Main Authors: Phan, Giao Q., Touloukian, Christopher E., Yang, James C., Restifo, Nicholas P., Sherry, Richard M., Hwu, Patrick, Topalian, Suzanne L., Schwartzentruber, Douglas J., Seipp, Claudia A., Freezer, Linda J., Morton, Kathleen E., Mavroukakis, Sharon A., White, Donald E., Rosenberg, Steven A.
Format: Artigo
Jezik:Inglês
Izdano: 2003
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1679660/
https://ncbi.nlm.nih.gov/pubmed/12843797
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