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Adenovirus Fiber Shaft Contains a Trimerization Element That Supports Peptide Fusion for Targeted Gene Delivery

Adenoviral (Ad) vectors have been widely used in human gene therapy clinical trials. However, their application has frequently been restricted by the unfavorable expression of cell surface receptors critical for Ad infection. Infections by Ad2 and Ad5 are largely regulated by the elongated fiber pro...

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Detalhes bibliográficos
Main Authors: Li, Jiali, Lad, Sonya, Yang, Guang, Luo, Yunping, Iacobelli-Martinez, Milena, Primus, F. James, Reisfeld, Ralph A., Li, Erguang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1676309/
https://ncbi.nlm.nih.gov/pubmed/17020947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01331-06
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