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Dependence of Adenovirus Infectivity on Length of the Fiber Shaft Domain

One of the objectives in adenovirus (Ad) vector development is to target gene delivery to specific cell types. Major attention has been given to modification of the Ad fiber knob, which is thought to determine virus tropism. However, among the human Ad serotypes with different tissue tropisms, not o...

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Detalles Bibliográficos
Main Authors: Shayakhmetov, Dmitry M., Lieber, André
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC110901/
https://ncbi.nlm.nih.gov/pubmed/11044071
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