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Dependence of Adenovirus Infectivity on Length of the Fiber Shaft Domain

One of the objectives in adenovirus (Ad) vector development is to target gene delivery to specific cell types. Major attention has been given to modification of the Ad fiber knob, which is thought to determine virus tropism. However, among the human Ad serotypes with different tissue tropisms, not o...

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Bibliographic Details
Main Authors: Shayakhmetov, Dmitry M., Lieber, André
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC110901/
https://ncbi.nlm.nih.gov/pubmed/11044071
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