Adenovirus Fiber Shaft Contains a Trimerization Element That Supports Peptide Fusion for Targeted Gene Delivery

Adenoviral (Ad) vectors have been widely used in human gene therapy clinical trials. However, their application has frequently been restricted by the unfavorable expression of cell surface receptors critical for Ad infection. Infections by Ad2 and Ad5 are largely regulated by the elongated fiber pro...

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Main Authors: Li, Jiali, Lad, Sonya, Yang, Guang, Luo, Yunping, Iacobelli-Martinez, Milena, Primus, F. James, Reisfeld, Ralph A., Li, Erguang
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2006
Teme:
Gene Delivery
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1676309/
https://ncbi.nlm.nih.gov/pubmed/17020947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01331-06
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