Učitavanje...
Different flecainide sensitivity of hNa(v)1.4 channels and myotonic mutants explained by state-dependent block
Flecainide, a class IC antiarrhythmic, was shown to improve myotonia caused by sodium channel mutations in situations where the class IB antiarrhythmic drug mexiletine was less efficient. Yet little is known about molecular interactions between flecainide and human skeletal muscle sodium (hNa(v)1.4)...
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| Glavni autori: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Blackwell Science Inc
2004
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1664778/ https://ncbi.nlm.nih.gov/pubmed/14608015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.046995 |
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