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Molecular determinants of differential pore blocking of kidney CLC-K chloride channels

The highly homologous Cl(−) channels CLC-Ka and CLC-Kb are important for water and salt conservation in the kidney and for the production of endolymph in the inner ear. Mutations in CLC-Kb lead to Bartter's syndrome and mutations in the small CLC-K subunit barttin lead to Bartter's syndrom...

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Detalhes bibliográficos
Main Authors: Picollo, Alessandra, Liantonio, Antonella, Didonna, Maria Paola, Elia, Laura, Camerino, Diana Conte, Pusch, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1299079/
https://ncbi.nlm.nih.gov/pubmed/15167890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400169
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