Llwytho...

Alkaline pH Block of CLC-K Kidney Chloride Channels Mediated by a Pore Lysine Residue

CLC-K chloride channels are expressed in the kidney and the inner ear, where they are involved in NaCl reabsorption and endolymph production, respectively. These channels require the beta subunit barttin for proper function. Mutations in ClC-Kb and barttin, lead to Bartter’s syndrome. Block of CLC-K...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gradogna, Antonella, Pusch, Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Biophysical Society 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699751/
https://ncbi.nlm.nih.gov/pubmed/23823226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.05.044
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