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Alkaline pH Block of CLC-K Kidney Chloride Channels Mediated by a Pore Lysine Residue
CLC-K chloride channels are expressed in the kidney and the inner ear, where they are involved in NaCl reabsorption and endolymph production, respectively. These channels require the beta subunit barttin for proper function. Mutations in ClC-Kb and barttin, lead to Bartter’s syndrome. Block of CLC-K...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Biophysical Society
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3699751/ https://ncbi.nlm.nih.gov/pubmed/23823226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.05.044 |
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