Dysfunction of human Rad18 results in defective postreplication repair and hypersensitivity to multiple mutagens

Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. The yeast Saccharomyces cerevisiae Rad18 protein plays a pivotal role in the process together with the Rad6 protein. Here, we have cloned a human homologue of RAD18, hRAD18. It maps on chromosome 3p24...

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Main Authors: Tateishi, Satoshi, Sakuraba, Yoshiyuki, Masuyama, Sadaharu, Inoue, Hirokazu, Yamaizumi, Masaru
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2000
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC16647/
https://ncbi.nlm.nih.gov/pubmed/10884424
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