Dysfunction of human Rad18 results in defective postreplication repair and hypersensitivity to multiple mutagens

Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. The yeast Saccharomyces cerevisiae Rad18 protein plays a pivotal role in the process together with the Rad6 protein. Here, we have cloned a human homologue of RAD18, hRAD18. It maps on chromosome 3p24...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Tateishi, Satoshi, Sakuraba, Yoshiyuki, Masuyama, Sadaharu, Inoue, Hirokazu, Yamaizumi, Masaru
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16647/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10884424/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.14.7927
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