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A ring of eight conserved negatively charged amino acids doubles the conductance of BK channels and prevents inward rectification

Large-conductance Ca(2+)–voltage-activated K(+) channels (BK channels) control many key physiological processes, such as neurotransmitter release and muscle contraction. A signature feature of BK channels is that they have the largest single channel conductance of all K(+) channels. Here we examine...

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Detalhes bibliográficos
Main Authors: Brelidze, Tinatin I., Niu, Xiaowei, Magleby, Karl L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC166430/
https://ncbi.nlm.nih.gov/pubmed/12843404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1532257100
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