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Stepwise contribution of each subunit to the cooperative activation of BK channels by Ca(2+)

BK channels (Slo1) are widely distributed K(+) channels that control Ca(2+)-dependent processes and cellular excitability. Their activation by intracellular Ca(2+) (Ca [Formula: see text]) is highly cooperative, with Hill coefficients of typically 2–5. To investigate the cooperativity contributed by...

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Detalhes bibliográficos
Main Authors: Niu, Xiaowei, Magleby, Karl L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC123275/
https://ncbi.nlm.nih.gov/pubmed/12161564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.172254699
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