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Slo1 Tail Domains, but Not the Ca(2+) Bowl, Are Required for the β1 Subunit to Increase the Apparent Ca(2+) Sensitivity of BK Channels

Functional large-conductance Ca(2+)- and voltage-activated K(+) (BK) channels can be assembled from four α subunits (Slo1) alone, or together with four auxiliary β1 subunits to greatly increase the apparent Ca(2+) sensitivity of the channel. We examined the structural features involved in this modul...

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Detalhes bibliográficos
Main Authors: Qian, Xiang, Nimigean, Crina M., Niu, Xiaowei, Moss, Brenda L., Magleby, Karl L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229562/
https://ncbi.nlm.nih.gov/pubmed/12451052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.20028692
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