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The β Subunit Increases the Ca(2+) Sensitivity of Large Conductance Ca(2+)-activated Potassium Channels by Retaining the Gating in the Bursting States
Coexpression of the β subunit (K(V),(Ca)β) with the α subunit of mammalian large conductance Ca(2+)- activated K(+) (BK) channels greatly increases the apparent Ca(2+) sensitivity of the channel. Using single-channel analysis to investigate the mechanism for this increase, we found that the β subuni...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
1999
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2222905/ https://ncbi.nlm.nih.gov/pubmed/10051518 |
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