Natural selection of more designable folds: A mechanism for thermophilic adaptation
An open question of great interest in biophysics is whether variations in structure cause protein folds to differ in the number of amino acid sequences that can fold to them stably, i.e., in their designability. Recently, we have shown that a novel quantitative measure of a fold's tertiary topology,...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2003
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166380/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12843403/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1530713100 |
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