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Natural selection of more designable folds: A mechanism for thermophilic adaptation

An open question of great interest in biophysics is whether variations in structure cause protein folds to differ in the number of amino acid sequences that can fold to them stably, i.e., in their designability. Recently, we have shown that a novel quantitative measure of a fold's tertiary topo...

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主要な著者: England, Jeremy L., Shakhnovich, Boris E., Shakhnovich, Eugene I.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC166380/
https://ncbi.nlm.nih.gov/pubmed/12843403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1530713100
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