Identification of a Unique Core Domain of Par-4 Sufficient for Selective Apoptosis Induction in Cancer Cells

Recent studies indicated that the leucine zipper domain protein Par-4 induces apoptosis in certain cancer cells by activation of the Fas prodeath pathway and coparallel inhibition of NF-κB transcriptional activity. However, the intracellular localization or functional domains of Par-4 involved in ap...

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Main Authors: El-Guendy, Nadia, Zhao, Yanming, Gurumurthy, Sushma, Burikhanov, Ravshan, Rangnekar, Vivek M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
Gene Expression
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC166354/
https://ncbi.nlm.nih.gov/pubmed/12897127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.16.5516-5525.2003
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