Phosphorylation of Par-4 by Protein Kinase A Is Critical for Apoptosis

Despite distinct dissimilarities, diverse cancers express several common protumorigenic traits. We present here evidence that the proapoptotic protein Par-4 utilizes one such common tumorigenic trait to become selectively activated and induce apoptosis in cancer cells. Elevated protein kinase A (PKA...

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Detalhes bibliográficos
Main Authors: Gurumurthy, Sushma, Goswami, Anindya, Vasudevan, Krishna Murthi, Rangnekar, Vivek M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC544017/
https://ncbi.nlm.nih.gov/pubmed/15657440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.3.1146-1161.2005
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